Description

Boc-Ala-NH2 is a protected amino acid derivative, specifically N-tert-butoxycarbonyl-L-alaninamide, widely used as a key building block in peptide synthesis. Its primary value lies in providing a stable, orthogonal protecting group for the α-amino function of alanine, enabling controlled elongation of peptide chains. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors developing novel therapeutic peptides and peptidomimetics.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental monomer for the automated, stepwise construction of custom peptide sequences in drug discovery and research.
• Solution-Phase Peptide Synthesis: Used in classical coupling reactions for producing specific peptide fragments or smaller-scale custom peptides.
• Pharmaceutical Intermediate: Serves as a critical raw material in the synthesis of active pharmaceutical ingredients (APIs) for peptide-based therapeutics.
• Bioconjugation and Labeling: Acts as a starting point for creating labeled peptides or peptide conjugates used in diagnostic assays and imaging probes.
• Academic and Industrial R&D: Employed in research laboratories for studying protein-protein interactions, enzyme substrates, and structure-activity relationships (SAR).
• Production of Peptide Libraries: Utilized in combinatorial chemistry to generate diverse arrays of peptides for high-throughput screening against biological targets.

Basic Information

Product Name	Boc-Ala-NH2
CAS No.	85642-13-3
Molecular Formula	C8H16N2O3
Molecular Weight	188.22 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-L-alaninamide; Boc-L-alaninamide; (S)-2-((tert-Butoxycarbonyl)amino)propanamide; tert-Butyloxycarbonyl-L-alaninamide; Boc-Ala-NH2; BOC-L-ALANINE AMIDE; N-Boc-L-alaninamide; N-α-tert-Butyloxycarbonyl-L-alaninamide
EINECS	Contact for details

Quality Control

Our Boc-Ala-NH2 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity suitable for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as chiral purity, assay, and impurity profiles. Our quality commitment aligns with the standards required for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]20/D	-15.0° to -25.0° (c=1 in Methanol)
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.