Description

3-(Deacetoxy)Vecuronium is a key pharmaceutical intermediate and a derivative of the neuromuscular blocking agent Vecuronium Bromide. This compound is critical for research and development in the synthesis of advanced neuromuscular blocking agents and their analogs. It serves the needs of pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic institutions focused on anesthesiology and medicinal chemistry.

Application

• Pharmaceutical Intermediate: Primary building block in the synthesis of Vecuronium Bromide and related neuromuscular blocking agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new analogs with improved pharmacological profiles.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory submissions in API manufacturing.
• Process Development: Employed in optimizing synthetic routes and scaling up production for neuromuscular blocking drugs.
• Academic & Clinical Research: Utilized in studies investigating the mechanisms of action and metabolism of non-depolarizing muscle relaxants.

Basic Information

Item	Detail
Product Name	3-(Deacetoxy)Vecuronium
CAS No.	85639-52-7
Molecular Formula	C34H57N2O3+
Molecular Weight	541.84 g/mol
Synonyms	Vecuronium Impurity C; Norcuronium; 3-Desacetylvecuronium; 1-[(2β,3α,5α,16β)-3,17-Bis(acetyloxy)-2-(1-piperidinyl)androstan-16-yl]-1-methylpiperidinium; Pancuronium Derivative; 3'-Desacetylvecuronium; Org NC 45 Metabolite
EINECS	Contact for details

Quality Control

Our 3-(Deacetoxy)Vecuronium is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC purity assay, identification by spectroscopic methods (IR, NMR, MS), and control of specified impurities. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.