Description

Boc-Phe-Ala-Ala-p-Nitro-Phe-Phe-Val-Leu 4-Hydroxymethylpyr CAS NO 85603-97-0 is a synthetic, protected peptide sequence designed for advanced biochemical research and pharmaceutical development. This compound is a critical building block for the synthesis of complex peptides and peptidomimetics, offering precise control over molecular structure. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, proteomics, and the study of enzyme-substrate interactions.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel therapeutic peptides targeting various diseases.
• Protease Substrate Analog: Used in biochemical assays to study the activity and inhibition of specific proteolytic enzymes, such as chymotrypsin or subtilisin.
• Peptide Library Construction: An essential component in solid-phase peptide synthesis (SPPS) for creating diverse peptide libraries for high-throughput screening.
• Structure-Activity Relationship (SAR) Studies: Employed to investigate how modifications to a peptide backbone affect biological activity and stability.
• Bioconjugation & Labeling: The reactive 4-Hydroxymethylpyr moiety allows for site-specific conjugation with fluorescent dyes, biotin, or other reporter molecules.
• Academic & Industrial Research: A valuable tool for fundamental research in biochemistry, medicinal chemistry, and molecular biology.

Basic Information

Product Name	Boc-Phe-Ala-Ala-p-Nitro-Phe-Phe-Val-Leu 4-Hydroxymethylpyr
CAS No.	85603-97-0
Molecular Formula	C58H75N9O13
Molecular Weight	1106.3 g/mol
Synonyms	Boc-Phe-Ala-Ala-pNO2-Phe-Phe-Val-Leu-OPfp; t-Butyloxycarbonyl-Phenylalanyl-Alanyl-Alanyl-4-Nitro-Phenylalanyl-Phenylalanyl-Valyl-Leucyl 4-Hydroxymethylpyrrolidine; Boc-F-A-A-F(NO2)-F-V-L-OPfp; Protected Peptide Sequence; Peptide Building Block; CAS 85603-97-0; p-Nitro-Phe containing peptide derivative; Pentafluorophenyl ester peptide
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of Boc-Phe-Ala-Ala-p-Nitro-Phe-Phe-Val-Leu 4-Hydroxymethylpyr is characterized by advanced analytical techniques, including HPLC, NMR, and mass spectrometry, to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.