Description

Pth (1-44) (Human) is a synthetic peptide fragment corresponding to the N-terminal region of human parathyroid hormone. This high-purity reference standard is critical for research and development in endocrinology and metabolic bone disease studies. It serves as an essential tool for scientists and pharmaceutical developers working on calcium homeostasis, osteoporosis, and related therapeutic areas. The product is supplied with full analytical characterization to ensure reliable and reproducible experimental results.

Application

• Biomedical Research: Used as a reference standard in studies of parathyroid hormone (PTH) receptor binding, signaling pathways, and biological activity.
• Assay Development: Critical for the calibration and validation of immunoassays (ELISA, RIA) designed to detect and quantify PTH or its fragments.
• Drug Discovery: Serves as a key intermediate or reference compound in the development of PTH-based therapeutics for osteoporosis and hypoparathyroidism.
• Structure-Activity Relationship (SAR) Studies: Utilized to investigate the functional domains of the full-length PTH hormone and to design peptide analogs.
• Quality Control: Employed as a system suitability standard in the pharmaceutical quality control of PTH-related peptide APIs and finished products.
• Academic Research: Supports fundamental research in bone metabolism, renal function, and endocrine regulation at universities and research institutes.

Basic Information

Product Name	Pth (1-44) (Human)
CAS No.	85568-24-7
Molecular Formula	C212H347N65O63S2
Molecular Weight	~5107.9 g/mol
Synonyms	Parathyroid Hormone (1-44), human; hPTH(1-44); PTH 1-44; Parathyrin (1-44); PTH human fragment 1-44; Teriparatide related peptide; N-terminal parathyroid hormone; CAS 85568-24-7
EINECS	Contact for details

Quality Control

Every batch of Pth (1-44) (Human) is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), peptide content, amino acid analysis, and mass spectrometry (MS) data is provided with each shipment to support your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Molecular weight confirmed by mass spectrometry
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by amino acid analysis)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.