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6-Amino-2,5-Dihydro-2-(-D-Ribofuranosyl)-4H-Pyrazolo[3,4-D]Pyrimidin-4-One CAS NO 85426-86-4


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CAS No.:85426-86-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

6-Amino-2,5-Dihydro-2-(-D-Ribofuranosyl)-4H-Pyrazolo[3,4-D]Pyrimidin-4-One is a high-purity nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block for the synthesis of novel antiviral and anticancer agents, particularly those targeting nucleic acid metabolism. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require reliable, high-quality intermediates for complex synthetic pathways and drug discovery programs.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of nucleoside-based antiviral and anticancer drugs.
  • Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to purine metabolism and nucleic acid synthesis.
  • Antiviral Drug Development: Serves as a core scaffold for developing novel therapeutics against viral infections.
  • Oncology Research: Investigated for its potential in creating targeted cancer therapies that interfere with DNA/RNA replication.
  • Proteomics & Genomics: Utilized in the study of nucleic acid-protein interactions and as a modified base in oligonucleotide synthesis.
  • Reference Standard: Employed as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name 6-Amino-2,5-Dihydro-2-(-D-Ribofuranosyl)-4H-Pyrazolo[3,4-D]Pyrimidin-4-One
CAS No. 85426-86-4
Molecular Formula C10H13N5O5
Molecular Weight 283.24 g/mol
Synonyms 6-Amino-2,5-dihydro-2-β-D-ribofuranosyl-4H-pyrazolo[3,4-d]pyrimidin-4-one; 2-β-D-Ribofuranosyl-4H-pyrazolo[3,4-d]pyrimidin-4-one, 6-amino-2,5-dihydro-; 6-Amino-2,5-dihydro-2-(β-D-ribofuranosyl)-4H-pyrazolo[3,4-d]pyrimidin-4-one; 6-Amino-2-(β-D-ribofuranosyl)-2,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one; Ribofuranosylpyrazolopyrimidinone; Contact for additional synonyms.
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Quality Control

Our 6-Amino-2,5-Dihydro-2-(-D-Ribofuranosyl)-4H-Pyrazolo[3,4-D]Pyrimidin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing batch-specific results are available upon request, supporting your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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