Description

4-Chloro-6-(Methylthio)-1H-Pyrazolo[3,4-D]Pyrimidine is a high-value heterocyclic building block and key synthetic intermediate. This compound matters for its role as a versatile scaffold in medicinal chemistry, enabling the development of novel therapeutic agents. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers focused on creating purine nucleoside analogs and kinase inhibitors.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of purine nucleoside analogs and kinase-targeted drug candidates.
• Agrochemical Research: Used in the development of novel herbicides and fungicides due to its bioactive heterocyclic core.
• Biochemical Tool Compound: Serves as a starting material for synthesizing enzyme inhibitors and probes for biological pathway studies.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions and further functionalization to create diverse pyrazolo[3,4-d]pyrimidine libraries.
• Material Science Research: Investigated as a potential component in the design of organic electronic materials and ligands for metal complexes.

Basic Information

Product Name	4-Chloro-6-(Methylthio)-1H-Pyrazolo[3,4-D]Pyrimidine
CAS No.	85426-79-5
Molecular Formula	C6H5ClN4S
Molecular Weight	200.65 g/mol
Synonyms	4-Chloro-6-(methylthio)-1H-pyrazolo[3,4-d]pyrimidine; 4-Chloro-6-methylsulfanyl-1H-pyrazolo[3,4-d]pyrimidine; 1H-Pyrazolo[3,4-d]pyrimidine, 4-chloro-6-(methylthio)-; 4-Chloro-6-methylmercapto-1H-pyrazolo[3,4-d]pyrimidine; 6-(Methylthio)-4-chloro-1H-pyrazolo[3,4-d]pyrimidine; 4-Chloro-6-(methylthio)pyrazolo[3,4-d]pyrimidine; 4-Chloro-6-methylthio-1H-pyrazolo[3,4-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-(Methylthio)-1H-Pyrazolo[3,4-D]Pyrimidine is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development. Certificates of Analysis (COA) with full specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.