Description

Thymosin Beta(4)Alanine is a synthetic, modified peptide analog of the naturally occurring Thymosin β-4, a key regulator of actin polymerization and cellular repair processes. This engineered variant offers enhanced stability and specific biological activity profiles for advanced research and development applications. It is primarily utilized by biotechnology, pharmaceutical, and advanced life science sectors for studying wound healing, tissue regeneration, and anti-inflammatory mechanisms.

Application

• Biopharmaceutical R&D: Used as a reference standard and active ingredient in preclinical studies for regenerative medicine, including wound healing and cardiac repair formulations.
• Cell Culture & Tissue Engineering: Employed to promote cell migration, proliferation, and differentiation in in vitro models of tissue regeneration.
• Cosmeceutical Research: Investigated for its potential anti-inflammatory and skin-repair properties in the development of high-end skincare and therapeutic dermatological products.
• Biochemical Research: Serves as a critical tool for studying actin dynamics, cellular signaling pathways, and the molecular mechanisms of the Thymosin β-4 protein family.
• Veterinary Medicine Development: Explored for applications in animal health, particularly for equine and companion animal tissue repair therapies.
• Diagnostic Reagent Component: May be used in the development of immunoassays and diagnostic kits targeting pathways related to tissue damage and repair.

Basic Information

Product Name	Thymosin Beta(4)Alanine
CAS No.	85410-66-8
Molecular Formula	C212H350N56O78S
Molecular Weight	~4963.5 g/mol
Synonyms	TB-500 (Alanine variant); Thymosin β4 Ala; Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser; Tβ4-Ala; Modified Thymosin β-4; LKKTETQEKNPLPSKETIEQEKQAGES (Alanine variant); AcSDKP-DM-AEIKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES
EINECS	Contact for details

Quality Control

Our Thymosin Beta(4)Alanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis, to ensure it meets stringent specifications for research and development use. Certificates of Analysis (COA) detailing all test results are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant use and storage under inert atmosphere. Allow the vial to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Peptide Content	≥ 80.0%
Amino Acid Analysis	± 10% of theoretical
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC/IC)	≤ 10.0%
Bacterial Endotoxins	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.