Description

5-Phenylpyrimidine-2-Carboxylic Acid is a high-value heterocyclic building block and key intermediate in advanced organic synthesis. This compound is essential for the development of novel active pharmaceutical ingredients (APIs) and functional materials due to its versatile pyrimidine-carboxylic acid scaffold. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and plant growth regulators.
• Ligand Synthesis: Used in coordination chemistry for the preparation of chelating ligands in catalysis and material science.
• Material Science: Employed in the research and development of organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology: Acts as a probe or scaffold in the design of enzyme inhibitors and biochemical tools.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	5-Phenylpyrimidine-2-Carboxylic Acid
CAS No.	85386-20-5
Molecular Formula	C11H8N2O2
Molecular Weight	200.20 g/mol
Synonyms	2-Pyrimidinecarboxylic acid, 5-phenyl-; 5-Phenyl-2-pyrimidinecarboxylic acid; 5-Phenylpyrimidine-2-carboxylic acid; 2-Carboxy-5-phenylpyrimidine; 85386-20-5; 5-Phenyl-pyrimidine-2-carboxylic acid; 5-Phenyl-2-carboxypyrimidine
EINECS	Contact for details

Quality Control

Our 5-Phenylpyrimidine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.