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Dansyl-Alanyl-Alanyl-Phenylalanyl-Phenylalanine-3-(4-(n-Methyl)Pyridyl)-1-Propionate CAS NO 85353-23-7


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CAS No.:85353-23-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Dansyl-Alanyl-Alanyl-Phenylalanyl-Phenylalanine-3-(4-(n-Methyl)Pyridyl)-1-Propionate is a specialized, high-purity synthetic peptide derivative designed for advanced research and development applications. This compound is critical for scientists requiring precise, well-characterized biochemical tools for probing protein interactions and enzyme mechanisms. It is primarily utilized by researchers and developers in the pharmaceutical, biotechnology, and life sciences sectors for applications such as fluorescence labeling, protease substrate studies, and as a key intermediate in the synthesis of more complex bioactive molecules.

Application

  • Protease & Enzyme Substrate: Used as a specific, fluorescently-labeled substrate for studying the kinetics and inhibition of proteolytic enzymes like chymotrypsin and subtilisin.
  • Biochemical Research Reagent: Serves as a critical intermediate or standard in peptide synthesis and structure-activity relationship (SAR) studies.
  • Fluorescence Labeling & Detection: The dansyl fluorophore enables sensitive detection and tracking in fluorescence spectroscopy, microscopy, and assay development.
  • Pharmaceutical R&D: Employed in drug discovery programs targeting proteases, aiding in the design and screening of novel therapeutic candidates.
  • Diagnostic Development: Can be incorporated into diagnostic assays and kits for detecting specific enzymatic activities.

Basic Information

Product Name Dansyl-Alanyl-Alanyl-Phenylalanyl-Phenylalanine-3-(4-(n-Methyl)Pyridyl)-1-Propionate
CAS No. 85353-23-7
Molecular Formula C46H52N6O8S
Molecular Weight 849.01 g/mol
Synonyms Dns-Ala-Ala-Phe-Phe-OP4M; Dansyl-A-A-F-F-OP4M; DAAAFF-OP4M; 5-(Dimethylamino)naphthalene-1-sulfonyl-Ala-Ala-Phe-Phe-3-(4-(N-Methyl)pyridinium-1-yl)propionate; Nα-(5-Dimethylaminonaphthalene-1-sulfonyl)-L-alanyl-L-alanyl-L-phenylalanyl-L-phenylalanine 3-[4-(N-methyl)pyridinio]propionate; Protease Substrate IV (Fluorogenic); Chymotrypsin Substrate (Dansylated)
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Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of Dansyl-Alanyl-Alanyl-Phenylalanyl-Phenylalanine-3-(4-(n-Methyl)Pyridyl)-1-Propionate is characterized using advanced analytical techniques including HPLC, mass spectrometry, and NMR to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool environment. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions, moisture, or light may lead to degradation. For long-term stability, store desiccated under inert atmosphere.

Specification

Item Specification
Appearance Off-white to light yellow solid
Identification (HPLC) Conforms to reference standard
Identification (MS) Conforms to structure
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 3.0%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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