Description

2,4-Di-sec-Butoxy-5-Fluoro-Pyrimidine is a high-purity fluorinated pyrimidine derivative, a crucial building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is essential for research and production facilities in the pharmaceutical, agrochemical, and fine chemical industries seeking reliable, high-quality intermediates for nucleoside and heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides containing fluoropyrimidine motifs.
• Fine Chemical Production: Serves as a building block for specialty chemicals, dyes, and liquid crystals.
• Research & Development: Critical for medicinal chemistry programs exploring new fluorinated heterocyclic compounds.
• Nucleoside Chemistry: Employed in the modification of nucleosides for potential therapeutic applications.
• Contract Manufacturing: Supplied to CDMOs for use in custom synthesis and scale-up projects.

Basic Information

Product Name	2,4-Di-sec-Butoxy-5-Fluoro-Pyrimidine
CAS No.	85326-28-9
Molecular Formula	C12H21FN2O2
Molecular Weight	244.31 g/mol
Synonyms	5-Fluoro-2,4-bis(sec-butoxy)pyrimidine; 2,4-Bis(1-methylpropoxy)-5-fluoropyrimidine; 5-Fluoro-2,4-di-sec-butoxypyrimidine; 85326-28-9; Pyrimidine, 5-fluoro-2,4-bis(1-methylpropoxy)-; 2,4-Di(sec-butoxy)-5-fluoropyrimidine
EINECS	Contact for details

Quality Control

Our 2,4-Di-sec-Butoxy-5-Fluoro-Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications. Our quality commitment supports compliance with cGMP guidelines for pharmaceutical intermediates and other relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.