Description

3-(Trifluoromethyl)Benzal Chloride is a versatile organofluorine building block characterized by its reactive benzal chloride group and trifluoromethyl substituent. This compound is valued for its ability to introduce the trifluoromethylphenyl moiety into more complex molecular architectures, a key transformation in advanced synthetic chemistry. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediates: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring the bioisosteric and metabolically stable trifluoromethyl group.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides where the CF3 group enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a key raw material in the production of fluorine-containing liquid crystals for display technologies.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic substitutions, and as a scaffold for constructing complex fluorinated molecules in R&D settings.
• Polymer & Material Science: Acts as a monomer or modifier in the synthesis of specialty polymers with unique surface properties and chemical resistance.
• Dye & Pigment Intermediates: Utilized in the production of high-performance, light-fast fluorinated dyes and pigments.

Basic Information

Product Name	3-(Trifluoromethyl)Benzal Chloride
CAS No.	85301-66-2
Molecular Formula	C9H5Cl2F3
Molecular Weight	241.04 g/mol
Synonyms	α,α-Dichloro-3-(trifluoromethyl)toluene; 3-(Trifluoromethyl)benzylidene Chloride; (3-Trifluoromethylphenyl)dichloromethane; 1-(Dichloromethyl)-3-(trifluoromethyl)benzene; Benzene, 1-(dichloromethyl)-3-(trifluoromethyl)-; α,α-Dichloro-α-(3-trifluoromethylphenyl)methane
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Benzal Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including GC, HPLC, and NMR to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent hydrolysis. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.