Description

S-Carbobenzoxyglutathione is a protected derivative of the essential tripeptide antioxidant glutathione. This compound is a crucial synthetic intermediate and research tool, valued for its role in studying glutathione metabolism and developing novel bioactive molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications in peptide synthesis, biochemical research, and drug discovery.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of glutathione analogs and prodrugs for therapeutic development.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate glutathione S-transferase (GST) activity and related metabolic pathways.
• Peptide Synthesis: Serves as a protected precursor in solid-phase and solution-phase peptide synthesis, where the carbobenzoxy (Cbz) group provides selective protection.
• Reference Standard: Employed as an analytical standard in HPLC, LC-MS, and NMR for the quantification and identification of glutathione derivatives.
• Antioxidant Studies: A tool compound for exploring the mechanisms of cellular redox balance and oxidative stress.
• Prodrug Design: Utilized in the design of compounds that target glutathione-mediated detoxification systems in cells.

Basic Information

Product Name	S-Carbobenzoxyglutathione
CAS No.	85270-49-1
Molecular Formula	C19H25N3O8S
Molecular Weight	455.48 g/mol
Synonyms	N-(Benzyloxycarbonyl)-L-glutamyl-L-cysteinylglycine; Cbz-Glutathione; S-Carbobenzoxy-L-glutathione; Glutathione, S-(phenylmethyl) carbamate; Z-Glutathione; NSC 334684; γ-Glutamylcysteinylglycine S-carbobenzoxy; L-γ-Glutamyl-L-cysteinylglycine S-(phenylmethyl) carbamate
EINECS	Contact for details

Quality Control

Our S-Carbobenzoxyglutathione is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.