Description

Neurotensin-Related Hexapeptide CAS NO 85213-84-9 is a synthetic bioactive peptide fragment derived from the endogenous neuropeptide neurotensin. This compound is of significant value for research into neurotensin receptor (NTS1 and NTS2) signaling pathways and their physiological roles. It is primarily needed by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on neuroscience, metabolic disorders, and oncology.

Application

• Neuroscience Research: Used as a tool compound to study the role of neurotensin in the central nervous system, including its effects on dopamine modulation, pain perception, and thermoregulation.
• Pharmacological Studies: Serves as a reference standard or active agent in in vitro and in vivo assays to evaluate receptor binding affinity, agonist/antagonist activity, and signal transduction mechanisms.
• Drug Discovery & Development: Acts as a lead structure or intermediate for the design and synthesis of novel neurotensin receptor-targeting therapeutics for conditions like schizophrenia, Parkinson's disease, and cancer.
• Biochemical Analysis: Employed in the development and validation of analytical methods, such as HPLC and mass spectrometry, for peptide quantification and purity assessment.
• Cell Signaling Research: Utilized to investigate G-protein coupled receptor (GPCR) pathways and intracellular calcium mobilization in various cell lines.

Basic Information

Item	Detail
Product Name	Neurotensin-Related Hexapeptide
CAS No.	85213-84-9
Molecular Formula	C₃₃H₅₃N₁₁O₉
Molecular Weight	747.85 g/mol
Synonyms	Neurotensin (8-13); NT (8-13); Arg-Arg-Pro-Tyr-Ile-Leu; RRPYIL; Neurotensin hexapeptide; H-Arg-Arg-Pro-Tyr-Ile-Leu-OH; Neurotensin fragment 8-13; L-Leucine, L-arginyl-L-arginyl-L-prolyl-L-tyrosyl-L-isoleucyl-
EINECS	Contact for details

Quality Control

Our Neurotensin-Related Hexapeptide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all test results are provided to ensure compliance with research-grade standards and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Amino Acid Analysis	Within ± 10% of theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.