Description

2-Bromo-4-(Trifluoromethyl)Benzaldehyde is a versatile and high-value aromatic aldehyde building block. This compound is critical for introducing both bromine and trifluoromethyl functional groups into complex molecular architectures, enabling precise tuning of electronic and steric properties. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates, active ingredients, and novel materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and advanced polymers with specific optoelectronic properties.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom chemical synthesis services and scale-up projects under cGMP or ISO standards.

Basic Information

Product Name	2-Bromo-4-(Trifluoromethyl)Benzaldehyde
CAS No.	85118-24-7
Molecular Formula	C8H4BrF3O
Molecular Weight	253.02 g/mol
Synonyms	2-Bromo-α,α,α-trifluoro-p-tolualdehyde; 4-(Trifluoromethyl)-2-bromobenzaldehyde; 2-Bromo-4-trifluoromethylbenzaldehyde; Benzaldehyde, 2-bromo-4-(trifluoromethyl)-; 2-Bromo-α,α,α-trifluoro-4-methylbenzaldehyde; p-(Trifluoromethyl)-o-bromobenzaldehyde
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4-(Trifluoromethyl)Benzaldehyde is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure consistency and purity for your critical synthesis steps. A detailed Certificate of Analysis (COA) with specifications for identity, assay, and impurity profile (by GC/HPLC) is supplied with each shipment. Our quality systems support development through to commercial scale, adhering to relevant ISO and cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.