Description

2,5-Difluorobenzylamine is a versatile fluorinated aromatic amine building block of significant importance in advanced organic synthesis. Its value lies in the unique reactivity imparted by the benzylamine group and the strategic placement of fluorine atoms on the aromatic ring, which are critical for modulating the electronic properties, lipophilicity, and metabolic stability of target molecules. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing kinase inhibitors, CNS-active drugs, and other bioactive molecules where fluorine substitution is advantageous.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the difluorobenzyl moiety can enhance biological activity and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Fluorinated Fine Chemical Production: Acts as a starting material for synthesizing more complex fluorinated compounds used in various high-value chemical applications.

Basic Information

Product Name	2,5-Difluorobenzylamine
CAS No.	85118-06-5
Molecular Formula	C7H7F2N
Molecular Weight	143.13 g/mol
Synonyms	(2,5-Difluorophenyl)methanamine; 1-(Aminomethyl)-2,5-difluorobenzene; 2,5-Difluorobenzyl amine; α-Amino-2,5-difluorotoluene; 2,5-Difluoro-α-toluidine; Benzenemethanamine, 2,5-difluoro-; 2,5-DFBA
EINECS	Contact for details

Quality Control

Our 2,5-Difluorobenzylamine is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.