Description

Vasopressin, 1-Deamino-(2-(o-Methyl)Tyr)-4-Val-8-Arg- is a synthetic analogue of the endogenous hormone arginine vasopressin, specifically engineered to enhance its pharmacological profile. This compound is valued for its potent and selective agonist activity at vasopressin receptors, offering improved metabolic stability and duration of action compared to the native peptide. It is a critical intermediate and active pharmaceutical ingredient (API) for advanced research and development in endocrinology, cardiovascular physiology, and central nervous system disorders, serving pharmaceutical manufacturers, biotechnology firms, and academic research institutions globally.

Application

• Pharmaceutical API Development: Serves as a key active ingredient in the formulation of novel therapeutics targeting conditions like diabetes insipidus, septic shock, and bleeding disorders.
• Biomedical Research: Used as a precise pharmacological tool to study vasopressin receptor (V1a, V1b, V2) signaling pathways, cellular responses, and physiological mechanisms in vitro and in vivo.
• Preclinical Studies: Essential for pharmacokinetic, pharmacodynamic, and toxicology assessments in animal models to support Investigational New Drug (IND) applications.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development, validation, and batch testing of related peptide products.
• Peptide Chemistry & Conjugation: Acts as a sophisticated building block for further chemical modification, labeling, or conjugation to create targeted drug delivery systems or diagnostic probes.

Basic Information

Product Name	Vasopressin, 1-Deamino-(2-(o-Methyl)Tyr)-4-Val-8-Arg-
CAS No.	85114-98-3
Molecular Formula	C48H68N14O11S2
Molecular Weight	1049.3 g/mol
Synonyms	Desmopressin Impurity; [1-Deamino, 2-O-methyltyrosine, 4-valine, 8-arginine]-vasopressin; d(CH2)5[Tyr(Me)^2,Val^4,Arg^8]VP; V1a Vasopressin Receptor Agonist; (2-(o-Methyl)Tyr)-4-Val-8-Arg-Vasopressin; 1-Deamino-2-O-methyltyrosine-4-valine-8-arginine vasopressin; dDAVP Related Compound; Manning Compound
EINECS	Contact for details

Quality Control

Our Vasopressin, 1-Deamino-(2-(o-Methyl)Tyr)-4-Val-8-Arg- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards suitable for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.