Description

4-((6,7-Dihydro-5H-Cyclopentapyrimidin-4-Yl)Amino)Benzonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its fused pyrimidine-cyclopentane core structure. This compound is of significant value for its role as a key building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, including kinase inhibitors and other small-molecule drugs targeting various disease pathways.

Application

This specialized chemical intermediate serves critical functions in several advanced research and development sectors:

• Pharmaceutical Research & Development: As a core scaffold for designing and synthesizing new chemical entities (NCEs) with potential therapeutic activity.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop kinase inhibitors and other targeted therapies.
• Contract Research Organizations (CROs): Employed in custom synthesis and library production for high-throughput screening and drug discovery campaigns.
• Academic Research: Utilized in universities and research institutes for studying heterocyclic chemistry and developing novel synthetic methodologies.
• Biochemical Tool Development: Potential use in creating labeled probes or assay components for biological target identification and validation.

Basic Information

Product Name	4-((6,7-Dihydro-5H-Cyclopentapyrimidin-4-Yl)Amino)Benzonitrile
CAS No.	85073-83-2
Molecular Formula	C14H12N4
Molecular Weight	236.27 g/mol
Synonyms	4-((6,7-Dihydro-5H-cyclopenta[d]pyrimidin-4-yl)amino)benzonitrile; 4-[(6,7-Dihydro-5H-cyclopentapyrimidin-4-yl)amino]benzonitrile; Benzonitrile, 4-((6,7-dihydro-5H-cyclopentapyrimidin-4-yl)amino)-; 4-(6,7-Dihydro-5H-cyclopenta[d]pyrimidin-4-ylamino)benzonitrile; 4-(Cyclopentapyrimidin-4-ylamino)benzonitrile; CPAPB; 85073-83-2
EINECS	Contact for details

Quality Control

Our production of 4-((6,7-Dihydro-5H-Cyclopentapyrimidin-4-Yl)Amino)Benzonitrile adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided with every shipment. We support cGMP-compliant manufacturing for advanced pharmaceutical applications, ensuring traceability and regulatory readiness.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere if long-term stability is required. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.