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Lhrh, Ac-Delta(3)-Pro(1)-4-F-Phe(2)-Trp(3)-Lys(6)- CAS NO 84979-91-9
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CAS No.:84979-91-9
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Lhrh, Ac-Delta(3)-Pro(1)-4-F-Phe(2)-Trp(3)-Lys(6)- is a synthetic, fluorinated analog of the luteinizing hormone-releasing hormone (LHRH) peptide. This modified peptide is engineered for enhanced stability and receptor binding affinity, making it a critical research tool in endocrinology and oncology. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies for advanced studies in hormone-dependent mechanisms and therapeutic development.
Application
- Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) in the development of novel hormone therapies and diagnostics.
- Endocrinology Studies: Used in vitro and in vivo to investigate the structure-activity relationships (SAR) of LHRH receptor binding and signal transduction pathways.
- Oncology Research: Employed in preclinical studies targeting hormone-responsive cancers, such as prostate and breast cancer, to evaluate therapeutic efficacy.
- Peptide Chemistry & Biochemistry: Acts as a model compound for studying the effects of fluorination and other modifications on peptide stability, bioavailability, and metabolic resistance.
- Biomarker Development: Potential use in the development of assay kits and diagnostic tools for monitoring hormonal activity.
Basic Information
| Product Name | Lhrh, Ac-Delta(3)-Pro(1)-4-F-Phe(2)-Trp(3)-Lys(6)- |
| CAS No. | 84979-91-9 |
| Molecular Formula | C64H83FN14O12 |
| Molecular Weight | 1227.4 g/mol |
| Synonyms | Ac-Delta(3)-Pro(1)-4-F-Phe(2)-Trp(3)-Lys(6)-LHRH; Fluorinated LHRH Analog; LHRH Agonist Analog; [Ac-δ-Pro1, 4-F-D-Phe2, D-Trp3, D-Lys6]-LHRH; Gonadorelin (4-F-D-Phe2, D-Trp3, D-Lys6) analog; Luteinizing Hormone-Releasing Hormone Fluorinated Derivative; 84979-91-9; LHRH Fluoropeptide |
| EINECS | Contact for details |
Quality Control
Our Lhrh, Ac-Delta(3)-Pro(1)-4-F-Phe(2)-Trp(3)-Lys(6)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided to guarantee compliance with research-grade standards and support regulatory submissions.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, controlled environment. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white lyophilized powder |
| Identification (HPLC/MS) | Conforms to reference standard |
| Purity (HPLC) | ≥ 98.0% |
| Single Impurity (HPLC) | ≤ 1.0% |
| Amino Acid Analysis | Conforms to theoretical composition |
| Water Content (KF) | ≤ 5.0% |
| Peptide Content | ≥ 80.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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