Description

3-Ethyl-11-(4-Methylpiperazino)-10,11-Dihydrodibenzo(B,F)Thiepin Metha Nesulfonate Hemihydrate is a high-purity pharmaceutical intermediate and active ingredient of significant commercial importance. Its value lies in its specific chemical structure, which is critical for advanced pharmaceutical synthesis and research applications. This compound is primarily needed by manufacturers and R&D facilities in the pharmaceutical, biotechnology, and fine chemical sectors for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex active pharmaceutical ingredients (APIs).
• Neurological Research: Used in preclinical studies and development of compounds targeting the central nervous system.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in laboratories.
• Process Development: Employed in scaling up and optimizing synthetic routes for pharmaceutical manufacturing.
• Academic & Contract Research: Utilized in university and CRO settings for medicinal chemistry and pharmacological research programs.

Basic Information

Product Name	3-Ethyl-11-(4-Methylpiperazino)-10,11-Dihydrodibenzo(B,F)Thiepin Metha Nesulfonate Hemihydrate
CAS No.	84964-85-2
Molecular Formula	C22H29N3O3S2 • 0.5H2O
Molecular Weight	456.61 g/mol (anhydrous basis)
Synonyms	Zotepine Methanesulfonate Hemihydrate; Zotepine Mesylate Hemihydrate; 3-Ethyl-11-(4-methyl-1-piperazinyl)dibenzo[b,f]thiepin Methanesulfonate Hemihydrate; 2-[(8-Chlorodibenzo[b,f]thiepin-10-yl)oxy]-N,N-dimethylethanamine Methanesulfonate; Lodopin (brand name variant); FG-7051; NSC-339093
EINECS	Contact for details

Quality Control

Our 3-Ethyl-11-(4-Methylpiperazino)-10,11-Dihydrodibenzo(B,F)Thiepin Metha Nesulfonate Hemihydrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a dry environment and opened under conditions of low humidity to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5% (on anhydrous basis)
Water Content (KF)	1.5% - 3.0% (theoretical for hemihydrate ~2.0%)
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.