Description

2-Amino-3-Chloro-5-(Trifluoromethyl)Phenol is a high-purity, multifunctional aromatic intermediate featuring a unique trifluoromethyl group. This compound is valued for its role as a critical building block in the synthesis of advanced agrochemicals and pharmaceuticals, where it imparts desirable properties such as enhanced metabolic stability and lipophilicity. It is primarily sought by R&D chemists and process development teams in the fine chemical, agrochemical, and pharmaceutical industries for creating novel active ingredients and specialty materials.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl and chloro substituents.
• Pharmaceutical Building Block: Used in medicinal chemistry for the research and development of new drug candidates, particularly in areas requiring fluorinated motifs for improved efficacy.
• Dye and Pigment Synthesis: Serves as an intermediate in the production of specialized dyes, pigments, and optical brighteners due to its phenolic and amino functional groups.
• Liquid Crystal & OLED Materials: Employed in the development of electronic materials for displays, where its molecular structure contributes to desired electronic and alignment properties.
• Polymer Modification: Acts as a monomer or additive for creating specialty polymers with enhanced chemical resistance or specific functional characteristics.
• Cross-coupling Reactions: A valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing complex molecular architectures.

Basic Information

Product Name	2-Amino-3-Chloro-5-(Trifluoromethyl)Phenol
CAS No.	84960-10-1
Molecular Formula	C7H5ClF3NO
Molecular Weight	211.57 g/mol
Synonyms	3-Chloro-2-hydroxy-6-(trifluoromethyl)aniline; 2-Amino-3-chloro-α,α,α-trifluoro-p-cresol; 2-Hydroxy-6-trifluoromethyl-3-chloroaniline; 3-Chloro-2-hydroxy-6-trifluoromethylaniline; 2-Amino-3-chloro-5-trifluoromethylphenol; 6-Amino-2-chloro-α,α,α-trifluoro-m-cresol; Phenol, 2-amino-3-chloro-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Chloro-5-(Trifluoromethyl)Phenol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the stringent requirements of our global B2B clients. Certificates of Analysis (COA) documenting all critical parameters are available upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.