Description

Argipressin (4-9), (3-1')-Disulfide Cys(6)- CAS NO 84953-77-5 is a synthetic cyclic hexapeptide fragment of the neurohypophysial hormone arginine vasopressin (AVP). This compound is a critical intermediate and reference standard in advanced pharmaceutical research and development. It is primarily utilized by biopharmaceutical companies and research institutions focused on endocrinology, peptide therapeutics, and neurobiology. The specific disulfide bridge structure makes it essential for studying receptor binding, metabolic pathways, and developing novel peptide-based drugs.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of vasopressin-related compounds in drug development and quality control laboratories.
• Biochemical Research: Serves as a key intermediate or tool compound in studies investigating the structure-activity relationship (SAR) of vasopressin and its analogs.
• Peptide Synthesis: Acts as a protected fragment for the solid-phase or solution-phase synthesis of larger, more complex vasopressin analogs.
• Receptor Binding Assays: Employed in competitive binding studies to characterize vasopressin receptor subtypes (V1a, V1b, V2) and screen for potential antagonists or agonists.
• Metabolic Pathway Studies: Used to trace and understand the degradation and metabolic fate of vasopressin fragments in in vitro models.
• Diagnostic Development: Potential use in the development of immunoassays or other diagnostic tests for conditions related to vasopressin dysfunction.

Basic Information

Product Name	Argipressin (4-9), (3-1')-Disulfide Cys(6)-
CAS No.	84953-77-5
Molecular Formula	C24H38N8O7S2
Molecular Weight	614.74 g/mol
Synonyms	Argipressin (4-9); [Cys6]-Argipressin (4-9); Cyclo(Cys-Tyr-Phe-Gln-Asn-Cys); AVP(4-9); Vasopressin (4-9) fragment; Des-Glycinamide9-arginine8-vasopressin (4-9); H-Cys-Tyr-Phe-Gln-Asn-Cys-OH (cyclic 3-1', 6-1'' disulfide); Cyclic Cys-Tyr-Phe-Gln-Asn-Cys
EINECS	Contact for details

Quality Control

Every batch of Argipressin (4-9), (3-1')-Disulfide Cys(6)- is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to support its use in regulated environments. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request and include data from multiple orthogonal analytical techniques to confirm identity, purity, and composition.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular weight
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 97.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.