Description

Vasopressinase-Altered Vasopressin is a chemically modified analog of the endogenous neurohypophysial hormone, arginine vasopressin (AVP). This engineered compound is designed for advanced research into vasopressin receptor signaling pathways and the development of novel therapeutic agents. It is a critical reagent for pharmaceutical R&D, academic research, and biotechnology applications focused on endocrinology, cardiovascular physiology, and central nervous system disorders.

Application

• Biomedical Research: Used as a reference standard and active agent in studies investigating vasopressin receptor (V1a, V1b, V2) pharmacology and signal transduction.
• Drug Discovery & Development: Serves as a key intermediate or lead compound in the design of novel vasopressin receptor agonists and antagonists for therapeutic applications.
• Diagnostic Assay Development: Employed in the development and validation of immunoassays (ELISA, RIA) to measure vasopressin levels or detect vasopressinase activity.
• Enzymology Studies: Acts as a specific substrate for studying the kinetics and inhibition of vasopressinase (also known as placental leucine aminopeptidase, P-LAP).
• Metabolic Pathway Analysis: Utilized to investigate the metabolic stability, clearance, and degradation pathways of vasopressin analogs in vitro.
• Neuroscience Research: Applied in models studying the role of vasopressin in social behavior, stress response, memory, and autonomic regulation.

Basic Information

Product Name	Vasopressinase-Altered Vasopressin
CAS No.	84953-75-3
Molecular Formula	C46H65N13O12S2
Molecular Weight	1080.2 g/mol
Synonyms	1-(3-Mercaptopropanoic acid)-2-(O-methyl-L-tyrosine)-8-L-arginine vasopressin; [1-β-Mercapto-β,β-cyclopentamethylenepropionic acid), 2-(O-methyl)tyrosine, 8-arginine]vasopressin; Desmopressin Impurity; AVP Analog; Modified Arginine Vasopressin; Vasopressinase Substrate; P-LAP Substrate
EINECS	Contact for details

Quality Control

Our Vasopressinase-Altered Vasopressin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. For custom synthesis or specific purity requirements (e.g., >95%, >98%), please contact our technical team.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 90%
Water Content (KF)	≤ 5.0 %
Peptide Content	≥ 80% (by amino acid analysis)
Solubility	Soluble in water, acetic acid, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.