Description

L-Isovaline, n-Hydroxy- (9Ci) is a non-proteinogenic amino acid derivative characterized by its unique structural features, including a hydroxyl group on the nitrogen atom. This compound is of significant interest in advanced chemical synthesis and pharmaceutical research due to its potential as a chiral building block and its role in studying metabolic pathways. It is primarily utilized by research institutions and chemical manufacturers specializing in fine chemicals, peptide mimetics, and novel bioactive compound development.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs) and peptide-based therapeutics.
• Biochemical Research: Used as a standard or reagent in metabolic studies, enzyme inhibition assays, and investigations into amino acid transport and function.
• Fine Chemical Synthesis: Acts as a specialized building block for constructing complex organic molecules with specific stereochemistry in medicinal chemistry projects.
• Peptidomimetics: Incorporated into peptide analogs to enhance stability, bioavailability, or biological activity for drug discovery applications.
• Academic Research: Employed in universities and R&D labs for fundamental studies in organic chemistry, biochemistry, and chemical biology.

Basic Information

Product Name	L-Isovaline, n-Hydroxy- (9Ci)
CAS No.	84942-72-3
Molecular Formula	C5H11NO3
Molecular Weight	133.15 g/mol
Synonyms	N-Hydroxy-L-isovaline; (S)-2-Amino-2-methyl-3-hydroxybutanoic acid, N-hydroxy derivative; 2-Amino-2-methyl-3-hydroxybutanoic acid, N-hydroxy-, (S)-; L-2-Amino-2-methyl-3-hydroxybutanoic acid, N-hydroxy-; N-Hydroxyisovaline; Hydroxyaminoisovaline; (S)-N-Hydroxy-2-amino-2-methyl-3-hydroxybutyric acid
EINECS	Contact for details

Quality Control

Our L-Isovaline, n-Hydroxy- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm identity and stereochemical integrity. We provide full traceability and a Certificate of Analysis (COA) with every shipment, detailing all test results against our stringent in-house specifications. Our quality systems are designed to meet the demands of research and cGMP-grade manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.