Description

2-Amino-n-(8-(o-Fluorobenzyl)-3-β-Nortropanyl)-4-Methoxy-5-Pyrimidi Necarboxamide is a sophisticated organic compound belonging to the class of nortropane-based pyrimidine carboxamides. This molecule is of significant interest for its potential as a high-value pharmaceutical intermediate or research chemical in the development of novel therapeutic agents. It is primarily sought by organizations engaged in advanced medicinal chemistry, pharmacology research, and custom synthesis for drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates targeting neurological or other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize biological activity profiles.
• Biochemical Research: Acts as a tool compound for investigating specific receptor interactions or enzyme inhibition in vitro.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production for clinical trials.
• Reference Standard: Provides a high-purity standard for analytical method development and validation in quality control laboratories.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and chemical biology.

Basic Information

Product Name	2-Amino-n-(8-(o-Fluorobenzyl)-3-β-Nortropanyl)-4-Methoxy-5-Pyrimidi Necarboxamide
CAS No.	84936-80-1
Molecular Formula	C₂₄H₂₈FN₅O₂
Molecular Weight	437.51 g/mol
Synonyms	2-Amino-N-[8-[(2-fluorophenyl)methyl]-8-azabicyclo[3.2.1]oct-3-yl]-4-methoxy-5-pyrimidinecarboxamide; 8-(2-Fluorobenzyl)-3β-(2-amino-4-methoxy-5-pyrimidinecarboxamido)nortropane; 84936-80-1; 2-Amino-4-methoxy-N-(8-(2-fluorobenzyl)-8-azabicyclo[3.2.1]octan-3-yl)-5-pyrimidinecarboxamide; (3β)-N-(8-[(2-Fluorophenyl)methyl]-8-azabicyclo[3.2.1]oct-3-yl)-2-amino-4-methoxy-5-pyrimidinecarboxamide
EINECS	Contact for details

Quality Control

Our 2-Amino-n-(8-(o-Fluorobenzyl)-3-β-Nortropanyl)-4-Methoxy-5-Pyrimidi Necarboxamide is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications. For advanced applications, we support development of custom analytical methods and can supply material meeting research-grade or higher standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Long-term storage under inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.