Description

Proline, 5-Thioxo-, Ethyl Ester (9Ci) is a specialized proline derivative characterized by a thioxo (C=S) group at the 5-position and an ethyl ester moiety. This unique structure makes it a valuable synthetic intermediate and building block in advanced organic synthesis and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecules and exploring novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Peptidomimetic Research: Used in the design and synthesis of peptidomimetics and constrained peptides to improve metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a precursor in the development of new herbicides, fungicides, and plant growth regulators.
• Organocatalyst Development: Investigated as a potential scaffold or precursor for novel asymmetric organocatalysts.
• Chemical Biology Probes: Employed in the creation of activity-based probes and molecular tools for studying enzyme function and protein-protein interactions.
• Material Science: Explored as a monomer or additive for specialty polymers with unique properties.

Basic Information

Product Name	Proline, 5-Thioxo-, Ethyl Ester (9Ci)
CAS No.	84911-17-1
Molecular Formula	C7H11NO2S
Molecular Weight	173.23 g/mol
Synonyms	Ethyl 5-Thioxoproline-2-carboxylate; 5-Thioxoproline Ethyl Ester; 2-Carbethoxy-5-thiazolidinone; 4-Thiazolidinecarboxylic acid, 2-oxo-, ethyl ester; L-Proline, 5-thioxo-, ethyl ester; Ethyl 2-oxo-4-thiazolidinecarboxylate; 84911-17-1; 5-Thioxoproline ethyl ester
EINECS	Contact for details

Quality Control

Our Proline, 5-Thioxo-, Ethyl Ester (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as identity, purity, and impurity profiles. Our quality system is designed to meet the stringent requirements of our global customer base in advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.