Description

β-Endorphin, Arg(9,19,24,28,29)- is a synthetic, arginine-substituted analog of the endogenous neuropeptide β-endorphin. This engineered peptide is crucial for advanced research in neurobiology and pharmacology, offering enhanced stability and specific receptor interaction profiles compared to the native sequence. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on pain management, neuropsychiatric disorders, and peptide-based therapeutic development.

Application

• Neuroscience Research: Investigation of opioid receptor binding, signaling pathways, and the physiological role of endorphins.
• Pharmacological Studies: Serving as a reference standard or active compound in assays for analgesic efficacy and mechanism of action.
• Drug Discovery: A key intermediate or lead compound in the development of novel, non-addictive pain therapeutics.
• Biochemical Analysis: Used in chromatography (HPLC, LC-MS) as a standard for method development and validation.
• Cell-based Assays: Studying the effects on cell proliferation, immune modulation, and stress response in vitro.
• Academic & Clinical Research: Fundamental studies on stress, addiction, and mood regulation mechanisms.

Basic Information

Product Name	β-Endorphin, Arg(9,19,24,28,29)-
CAS No.	84779-04-4
Molecular Formula	C158H251N51O46S
Molecular Weight	3466.0 g/mol (approximately)
Synonyms	Arg(9,19,24,28,29)-β-Endorphin; β-Endorphin (Arg9,19,24,28,29); [Arg9,19,24,28,29]-β-Endorphin; H-Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr-Lys-Lys-Gly-Glu-OH; β-Endorphin, arginine-substituted analog; Synthetic β-endorphin analog
EINECS	Contact for details

Quality Control

Our β-Endorphin, Arg(9,19,24,28,29)- is manufactured under strict quality systems suitable for research and development. Each batch is characterized using advanced analytical techniques to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided, detailing results from HPLC, MS, and amino acid analysis. We support compliance with relevant guidelines for research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Molecular weight confirmed
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.