Description

4,6-Dichloro-2-(4-Methyl-Piperazin-1-Yl)-Pyrimidine is a high-value pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both chloro and methylpiperazinyl substituents, makes it an essential intermediate for the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is primarily sought by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the multi-step synthesis of complex APIs requiring a functionalized pyrimidine moiety.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for metal catalysis and other synthetic transformations.

Basic Information

Product Name	4,6-Dichloro-2-(4-Methyl-Piperazin-1-Yl)-Pyrimidine
CAS No.	84727-44-6
Molecular Formula	C9H11Cl2N5
Molecular Weight	248.12 g/mol
Synonyms	2,4-Dichloro-6-(4-methyl-1-piperazinyl)pyrimidine; 2-(4-Methylpiperazin-1-yl)-4,6-dichloropyrimidine; 4,6-Dichloro-2-(4-methyl-1-piperazinyl)pyrimidine; 4,6-Dichloro-2-(4-methylpiperazin-1-yl)pyrimidine; 84727-44-6; 4,6-Dichloro-2-(4-methylpiperazino)pyrimidine
EINECS	Contact for details

Quality Control

Our 4,6-Dichloro-2-(4-Methyl-Piperazin-1-Yl)-Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical and agrochemical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.