Description

n-[n-[N2,N6-Bis[(Benzyloxy)Carbonyl]-L-Lysyl]Glycyl]Glycine is a protected tripeptide derivative, specifically a key intermediate in solid-phase peptide synthesis (SPPS). This compound matters for its role in constructing complex peptide sequences, where it provides orthogonal protection for the lysine side chain, enabling precise and sequential coupling. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of peptide-based therapeutics, diagnostics, and biochemical tools.

Application

• Peptide Synthesis Intermediate: A crucial building block in the solid-phase synthesis of longer, complex peptides containing lysine residues.
• Pharmaceutical Research: Used in the research and development of novel peptide drugs, including hormones, enzyme inhibitors, and antimicrobial peptides.
• Bioconjugation Chemistry: Serves as a spacer or linker molecule in the conjugation of peptides to other biomolecules, dyes, or solid supports.
• Biochemical Reagent: Employed in enzymatic studies and as a substrate or inhibitor in protease and peptidase research.
• Custom Peptide Production: Essential for contract research and manufacturing organizations (CROs/CMOs) producing custom peptides for clients.
• Protecting Group Strategy: Demonstrates the application of benzyloxycarbonyl (Cbz) protecting groups for amine functionalities in multi-step organic synthesis.

Basic Information

Product Name	n-[n-[N2,N6-Bis[(Benzyloxy)Carbonyl]-L-Lysyl]Glycyl]Glycine
CAS No.	84697-19-8
Molecular Formula	C27H34N4O8
Molecular Weight	542.58 g/mol
Synonyms	H-Lys(Cbz-Cbz)-Gly-Gly-OH; Nα,Nε-Bis-Cbz-L-Lysyl-Glycyl-Glycine; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-((((benzyloxy)carbonyl)amino)hexanoic acid (Related Fmoc variant); Glycyl-glycyl-N2,N6-bis(benzyloxycarbonyl)-L-lysine; Cbz-Lys(Cbz)-Gly-Gly-OH; Z-Lys(Z)-Gly-Gly-OH; Fmoc-Lys(Cbz)-Gly-Gly-OH (Protected form); L-Lysine, N2,N6-bis[(phenylmethoxy)carbonyl]-, 1-[N-(glycylglycyl)]-
EINECS	Contact for details

Quality Control

Our n-[n-[N2,N6-Bis[(Benzyloxy)Carbonyl]-L-Lysyl]Glycyl]Glycine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and identity confirmation via mass spectrometry (MS) and infrared (IR) spectroscopy, to ensure it meets the high standards required for peptide synthesis. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent decomposition. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 5.0%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.