Description

Benzamide, n-((2,3-Dihydro-8-Methoxy-1-Methyl-5-(3-Thienyl)-1H-1,4-Benzodiazepin-2-Yl)Methyl)-, Monohydrochloride is a high-purity, specialized benzodiazepine derivative offered as a monohydrochloride salt. This compound is a critical pharmaceutical intermediate and research chemical, valued for its precise chemical structure which serves as a key building block in advanced synthetic pathways. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel therapeutic agents and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel benzodiazepine-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold or building block in drug discovery programs targeting central nervous system (CNS) disorders.
• Biochemical Research: Employed in studies investigating receptor-ligand interactions and pharmacological mechanisms.
• Reference Standard: Utilized as an analytical standard for quality control and method development in pharmaceutical analysis.
• Process Development: Applied in the optimization and scale-up of synthetic routes for complex organic molecules.

Basic Information

Product Name	Benzamide, n-((2,3-Dihydro-8-Methoxy-1-Methyl-5-(3-Thienyl)-1H-1,4-Benzodiazepin-2-Yl)Methyl)-, Monohydrochloride
CAS No.	84671-43-2
Molecular Formula	C23H24ClN3O2S
Molecular Weight	441.97 g/mol
Synonyms	1-Methyl-5-(3-thienyl)-8-methoxy-1,4-benzodiazepin-2-one-3-carboxamide Hydrochloride; 3-Carbamoyl-1-methyl-5-(3-thienyl)-8-methoxy-1,4-benzodiazepin-2-one Hydrochloride; 8-Methoxy-1-methyl-5-(3-thienyl)-1,4-benzodiazepine-2-carboxamide Hydrochloride; 5-(3-Thienyl)-8-methoxy-1-methyl-1,4-benzodiazepine-2-carboxamide Monohydrochloride; 1-Methyl-5-(thiophen-3-yl)-8-methoxy-1,4-benzodiazepine-2-carboxamide Hydrochloride; Ro 15-4513 Hydrochloride (common research name); GYKI-51189 Hydrochloride (common research name)
EINECS	Contact for details

Quality Control

Our Benzamide, n-((2,3-Dihydro-8-Methoxy-1-Methyl-5-(3-Thienyl)-1H-1,4-Benzodiazepin-2-Yl)Methyl)-, Monohydrochloride is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%; Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.