Description

2,5-Dibromo-4-(trifluoromethoxy)aniline is a specialized halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring bromine and trifluoromethoxy substituents, makes it a valuable precursor for creating complex molecules with tailored electronic and steric properties. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the trifluoromethoxy group enhances biological activity and metabolic stability.
• Material Science: Serves as a monomer or functionalization agent in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Manufacturing: Acts as a precursor for synthesizing complex, high-performance dyes and pigments with specific color fastness and stability properties.
• Cross-Coupling Reactions: An important substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing biaryl and complex aromatic systems.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	2,5-Dibromo-4-(trifluoromethoxy)aniline
CAS No.	84483-32-9
Molecular Formula	C7H4Br2F3NO
Molecular Weight	348.92 g/mol
Synonyms	4-Amino-2,5-dibromo-1-(trifluoromethoxy)benzene; 2,5-Dibromo-4-(trifluoromethoxy)benzenamine; 2,5-Dibromo-α,α,α-trifluoro-p-anisidine; 1-Amino-2,5-dibromo-4-(trifluoromethoxy)benzene; Benzenamine, 2,5-dibromo-4-(trifluoromethoxy)-; 2,5-Dibromo-4-trifluoromethoxyaniline
EINECS	Contact for details

Quality Control

Our 2,5-Dibromo-4-(trifluoromethoxy)aniline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to confirm identity and purity. Certificates of Analysis (COA) detailing all test results are provided with every shipment. We support custom synthesis and can tailor specifications to meet specific project requirements, including compliance with ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.