Description

n-Trifluoroacetyl-L-G-Glutamyl-L-Cysteine Dimethyl Ester, (2-2') Disulphide is a specialized, high-purity synthetic peptide derivative designed for advanced research and development applications. This compound serves as a critical building block and key intermediate in the synthesis of complex biomolecules, offering precise structural control. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic research institutions focused on peptide chemistry, drug discovery, and biochemical studies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel peptide-based therapeutics and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a model compound or a protected intermediate in studies of disulfide bond formation, peptide folding, and enzyme-substrate interactions.
• Proteomics & Peptide Synthesis: Employed in solid-phase and solution-phase peptide synthesis (SPPS) for constructing peptides with specific cysteine linkages.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in HPLC and LC-MS analysis within QC laboratories.
• Drug Discovery Platforms: Integrated into combinatorial chemistry libraries for screening against biological targets to identify new lead compounds.

Basic Information

Product Name	n-Trifluoroacetyl-L-G-Glutamyl-L-Cysteine Dimethyl Ester, (2-2') Disulphide
CAS No.	84344-30-9
Molecular Formula	C22H30F6N4O10S2
Molecular Weight	688.61 g/mol
Synonyms	N-[(N2-Trifluoroacetyl-L-γ-glutamyl)-S-(dimethoxyphosphinyl)-L-cysteinyl]glycine Dimethyl Ester; L-Cysteine, N-[N-[N-[(trifluoroacetyl)-L-α-glutamyl]-S-[(dimethoxyphosphinyl)thio]-]-, dimethyl ester; TFAGCG(OMe)2 Disulfide; N-TFA-γ-Glu-Cys(OMe)-Gly-OMe Disulfide; (2S,2'S)-2,2'-Disulfanediylbis(1-((2S)-4-((dimethoxyphosphoryl)thio)-2-((2S)-4-methoxy-4-oxo-2-((trifluoroacetyl)amino)butanamido)butanamido)-3-oxopropane-1,1-diyl) diacetate (long-form IUPAC variant)
EINECS	Contact for details

Quality Control

Our n-Trifluoroacetyl-L-G-Glutamyl-L-Cysteine Dimethyl Ester, (2-2') Disulphide is manufactured under controlled conditions to ensure high chemical purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a desiccated environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.