Description

L-Bame CAS NO 84332-93-4 is a specialized chiral intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a key building block for the production of enantiomerically pure pharmaceuticals and fine chemicals. This compound is essential for research and manufacturing organizations in the pharmaceutical, agrochemical, and biotechnology sectors seeking to develop novel active ingredients with high stereochemical fidelity.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of chiral active pharmaceutical ingredients (APIs), particularly for neurological and metabolic disorders.
• Asymmetric Synthesis: Used as a chiral auxiliary or building block in catalytic asymmetric reactions to induce desired stereochemistry.
• Peptidomimetic Research: Serves as a constrained amino acid analog in the design and development of novel peptide-based therapeutics.
• Agrochemical Development: Employed in the research and production of enantiomerically pure herbicides and pesticides for enhanced efficacy and environmental safety.
• Ligand Synthesis: A starting material for creating chiral ligands used in homogeneous catalysis for industrial chemical processes.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research laboratories.

Basic Information

Product Name	L-Bame
CAS No.	84332-93-4
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	(S)-2-Azabicyclo[2.2.1]heptane-3-carboxylic acid, methyl ester; L-2-Azanorbornane-3-carboxylic acid methyl ester; Methyl (1S,2R,4S)-2-azabicyclo[2.2.1]heptane-3-carboxylate; L-BAME; (1S,2R,4S)-Methyl 2-azabicyclo[2.2.1]heptane-3-carboxylate; Bicyclic proline derivative; L-2-Azabicyclo[2.2.1]heptane-3-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our L-Bame is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as chiral purity, chemical purity, and impurity profiles. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your critical production and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.