Description

Argipressin, Asu(1,6)-Phe(4-N3)(3)- is a synthetic, azide-modified analog of the neurohypophysial hormone arginine vasopressin (AVP). This engineered peptide is a critical research tool for studying vasopressin receptor biology and signaling pathways through photoaffinity labeling techniques. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotech companies engaged in neuroendocrinology, cardiovascular research, and the development of novel therapeutic agents targeting the vasopressin system.

Application

• Photoaffinity Labeling Studies: Acts as a covalent probe for identifying and characterizing vasopressin V1a and V2 receptor binding sites and their structural domains.
• Receptor Mapping & Biochemistry: Essential for investigating receptor-ligand interactions, conformational changes, and the molecular mechanisms of vasopressin signaling.
• Drug Discovery Research: Used in the design and screening of new vasopressin receptor agonists and antagonists for potential therapeutic applications.
• Bioconjugation & Probe Development: Serves as a key intermediate for creating advanced diagnostic or targeted research probes due to its reactive azide group.
• Academic & Pharmaceutical R&D: Fundamental material for basic research in endocrinology, renal function, cardiovascular physiology, and central nervous system disorders.

Basic Information

Product Name	Argipressin, Asu(1,6)-Phe(4-N3)(3)-
CAS No.	84272-25-3
Molecular Formula	C46H65N15O12S2
Molecular Weight	1084.2 g/mol
Synonyms	[Asu1,6, Phe(4-N3)3]-Arginine Vasopressin; [1-(β-Mercapto-β,β-cyclopentamethylenepropionic acid), 6-L-α-aminosuberic acid, 3-(4-azido-L-phenylalanine)]-8-L-arginine Vasopressin; 4-Azido-Phe3-AVP; Photoactivatable AVP Analog; Azido-modified Argipressin; Vasopressin Azide Derivative; AVP Photoaffinity Label
EINECS	Contact for details

Quality Control

Our Argipressin, Asu(1,6)-Phe(4-N3)(3)- is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to GMP principles for peptide synthesis, ensuring traceability and reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%
Biological Activity	Assessed by receptor binding assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.