Description

Enkephalinamide-Leu, De-Tyr(1)-Ala(2)- CAS NO 84145-88-0 is a synthetic peptide analog derived from the enkephalin structure, specifically modified to study receptor interactions and metabolic stability. This compound is of significant value in biochemical and pharmacological research for investigating the structure-activity relationships of opioid peptides without the full analgesic profile. It is primarily needed by research institutions and pharmaceutical developers focused on neurobiology, peptide chemistry, and the development of novel therapeutic agents targeting the central nervous system.

Application

• Biochemical Research: Used as a reference standard and tool compound for studying enkephalin metabolism and degradation pathways.
• Pharmacological Studies: Employed in in vitro assays to investigate the binding affinity and selectivity of modified opioid peptide sequences at various receptor subtypes.
• Peptide Chemistry Development: Serves as a key intermediate or model compound in the synthesis and development of new peptide-based pharmaceuticals with enhanced stability.
• Neuroscience Research: Applied in studies exploring the physiological roles of endogenous opioid systems and their modulation.
• Analytical Standard: Utilized as a high-purity standard for method development and validation in analytical techniques like HPLC and mass spectrometry within quality control laboratories.

Basic Information

Product Name	Enkephalinamide-Leu, De-Tyr(1)-Ala(2)-
CAS No.	84145-88-0
Molecular Formula	C24H38N6O6
Molecular Weight	506.60 g/mol
Synonyms	De-Tyr(1)-Ala(2)-Leu-enkephalinamide; [Ala2, Leu5]-Enkephalinamide (des-Tyr1); H-Ala-Gly-Phe-Leu-NH2; Leu-enkephalinamide, De-Tyr(1)-Ala(2)-; AGFLa; AGFL-NH2; Opioid peptide fragment (4-7) amide; Tetrapeptide amide AGFLa
EINECS	Contact for details

Quality Control

Our Enkephalinamide-Leu, De-Tyr(1)-Ala(2)- is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and mass spectrometry for identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in water, DMSO, acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.