Description

2-Hydroxypropanesulphonyl Chloride is a versatile sulfonyl chloride derivative, a key reactive intermediate in organic synthesis. Its value lies in its ability to introduce the sulfonyl functional group, enabling the creation of compounds with enhanced biological activity or specific material properties. This chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity building blocks for advanced synthesis.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for sulfonamide-based drugs.
• Agrochemical Synthesis: Used in the production of modern herbicides, fungicides, and insecticides, where the sulfonyl moiety contributes to efficacy.
• Polymer Modification: Serves as a functionalizing agent to introduce sulfonyl groups into polymer chains, altering properties like solubility or reactivity.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of specialized sulfonated dyes and colorants.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry in developing new chemical entities.
• Ligand and Catalyst Preparation: Used to synthesize specialized ligands or catalyst components for asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	2-Hydroxypropanesulphonyl Chloride
CAS No.	84145-10-8
Molecular Formula	C₃H₇ClO₃S
Molecular Weight	158.60 g/mol
Synonyms	1-Hydroxy-2-propanesulfonyl chloride; 2-Hydroxy-1-propanesulfonyl chloride; α-Hydroxypropane sulfonyl chloride; 2-Hydroxypropane-1-sulfonyl chloride; Hydroxypropylsulfonyl chloride; Propane-1-sulfonyl chloride, 2-hydroxy-; 84145-10-8
EINECS	Contact for details

Quality Control

Our 2-Hydroxypropanesulphonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.