Description

Cyclo(Alanyl-Prolyl-Phenylalanyl-Proline) is a synthetic cyclic tetrapeptide with the CAS number 84107-30-2. This compound is of significant interest in pharmaceutical research and development due to its unique conformational constraints and potential biological activity. It serves as a valuable building block and reference standard for researchers in medicinal chemistry and peptide science. Target industries include pharmaceutical R&D, biotechnology, and fine chemical synthesis.

Application

• Pharmaceutical Research: Used as a key intermediate or reference standard in the development of novel peptide-based therapeutics.
• Medicinal Chemistry: Serves as a constrained scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Biochemical Research: Employed in enzymatic studies and as a tool compound to investigate peptide-protein interactions.
• Fine Chemical Synthesis: Acts as a specialized building block for the synthesis of more complex peptide architectures and libraries.
• Academic Research: Utilized in universities and research institutes for studying peptide conformation, stability, and bioactivity.

Basic Information

Product Name	Cyclo(Alanyl-Prolyl-Phenylalanyl-Proline)
CAS No.	84107-30-2
Molecular Formula	C25H32N4O5
Molecular Weight	468.55 g/mol
Synonyms	Cyclo(Ala-Pro-Phe-Pro); Cyclo(A-P-F-P); c(A-P-F-P); Cyclo(L-alanyl-L-prolyl-L-phenylalanyl-L-prolyl); Cyclic Tetrapeptide A-P-F-P; L-Alanyl-L-prolyl-L-phenylalanyl-L-prolyl, cyclic; 1,4-Diaza-2,5-dioxocyclohexane-1,4-dipropanamide, N1-(1-oxo-3-phenylpropyl)-L-prolyl-L-alanyl-; Cyclo(alanine-proline-phenylalanine-proline)
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, residual solvents, and related substances are available upon request. We adhere to cGMP principles for the manufacture of research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.