Description

1-Methyl-7-Chloro-5-Benzoylhydrazino-2,3-Dihydro-1H-1,4-Benzodiazepin- 2-One is a high-purity, specialized benzodiazepine derivative with significant value in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate for the creation of novel therapeutic agents targeting the central nervous system. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing next-generation anxiolytics, sedatives, and other neuroactive compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel benzodiazepine-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Reference Standard: Serves as an analytical standard for quality control and method development in pharmaceutical analysis.
• Preclinical Studies: Employed in the development and testing of new chemical entities (NCEs) for neurological and psychiatric disorders.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, non-commercial drug candidates.

Basic Information

Product Name	1-Methyl-7-Chloro-5-Benzoylhydrazino-2,3-Dihydro-1H-1,4-Benzodiazepin- 2-One
CAS No.	84044-26-8
Molecular Formula	C₁₇H₁₅ClN₄O₂
Molecular Weight	342.78 g/mol
Synonyms	7-Chloro-1-methyl-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one 5-benzoylhydrazone; 1-Methyl-7-chloro-5-(phenylcarbonylhydrazono)-2,3-dihydro-1H-1,4-benzodiazepin-2-one; 84044-26-8; Benzodiazepine derivative 84044-26-8; 5-Benzoylhydrazino-7-chloro-1-methyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one
EINECS	Contact for details

Quality Control

Our 1-Methyl-7-Chloro-5-Benzoylhydrazino-2,3-Dihydro-1H-1,4-Benzodiazepin- 2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical research applications. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.