Description

Metaclazepam is a benzodiazepine derivative, a class of compounds known for their significant pharmacological activity. This high-purity intermediate is critical for research and development in the pharmaceutical sector, enabling the synthesis of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on central nervous system (CNS) drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of novel benzodiazepine-based active pharmaceutical ingredients (APIs).
• Neurological Research: Used as a reference standard or precursor in preclinical studies investigating GABAA receptor modulation and related CNS pathways.
• Medicinal Chemistry: Serves as a core scaffold for the design and development of new chemical entities with potential anxiolytic, sedative, or muscle relaxant properties.
• Process Development: Employed in optimizing synthetic routes and scaling up production for advanced pharmaceutical compounds.
• Analytical Reference Standard: Utilized in quality control laboratories for method development, validation, and impurity profiling via HPLC, GC-MS, or NMR.

Basic Information

Product Name	Metaclazepam
CAS No.	84031-17-4
Molecular Formula	C17H15ClN2O2
Molecular Weight	314.77 g/mol
Synonyms	7-Chloro-1,3-dihydro-5-phenyl-1-(2-propynyl)-2H-1,4-benzodiazepin-2-one; 1-(2-Propynyl)-7-chloro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; Metaclazepamum; KC-2547; Talis
EINECS	Contact for details

Quality Control

Our Metaclazepam is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements of pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.