Description

Ozagrelhydrochloridehydrate CAS NO 83993-01-5 is a selective thromboxane A2 (TXA2) synthase inhibitor, a key pharmaceutical intermediate and active ingredient. Its primary value lies in its potent antiplatelet and vasodilatory properties, making it crucial for the development of treatments targeting thrombotic and ischemic conditions. This compound is essential for pharmaceutical R&D teams and manufacturers focused on cardiovascular and cerebrovascular therapeutics, as well as for researchers investigating TXA2-mediated pathways.

Application

• Pharmaceutical Active Ingredient (API): Primary use as the active component in antiplatelet and antithrombotic medications.
• Cardiovascular Drug Synthesis: A critical intermediate in the production of drugs designed to prevent and treat conditions like myocardial infarction and unstable angina.
• Cerebrovascular Drug Development: Used in the formulation of treatments for ischemic stroke and cerebral thrombosis.
• Biochemical Research: A vital tool for in vitro and in vivo studies on thromboxane A2 synthase inhibition and platelet aggregation mechanisms.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Preclinical and Clinical Studies: Employed in the development and testing stages of new therapeutic candidates targeting thrombosis.

Basic Information

Product Name	Ozagrelhydrochloridehydrate
CAS No.	83993-01-5
Molecular Formula	C13H12N2O2 • HCl • xH2O
Molecular Weight	264.71 (Anhydrous base)
Synonyms	Ozagrel HCl Hydrate; (E)-3-[4-(1H-Imidazol-1-ylmethyl)phenyl]-2-propenoic Acid Hydrochloride Hydrate; OKY-046 Hydrochloride Hydrate; Thromboxane A2 Synthase Inhibitor; Cataclot; Xanbon; 4-[(1H-Imidazol-1-yl)methyl]cinnamic Acid Hydrochloride Hydrate
EINECS	Contact for details

Quality Control

Our Ozagrelhydrochloridehydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identification by IR and NMR, and tests for residual solvents and related substances, ensuring compliance with pharmaceutical-grade standards. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5% (on anhydrous basis)
Water Content (KF)	As per hydrate specification
Related Substances (HPLC)	Total impurities ≤1.5%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.