Description

8-Chloro-6-(1-Methyl-4-Piperidyl)-6H-Dibenz(B,E)-1,4-Oxathiepin Hydrog En Maleate is a high-purity, complex organic compound primarily utilized as a key intermediate in advanced pharmaceutical synthesis. This compound matters for its critical role in the research and development of novel therapeutic agents, particularly within the central nervous system (CNS) and psychopharmacology domains. Pharmaceutical manufacturers and advanced research institutions need this material for developing new drug candidates, process optimization, and analytical method development.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel psychotropic and neuroactive drug candidates.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control in API manufacturing.
• Process Chemistry: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial production scales.
• Academic Research: Utilized in university and institutional labs for pharmacological studies and exploring new therapeutic pathways.

Basic Information

Product Name	8-Chloro-6-(1-Methyl-4-Piperidyl)-6H-Dibenz(B,E)-1,4-Oxathiepin Hydrog En Maleate
CAS No.	83986-04-3
Molecular Formula	C21H22ClNO4S
Molecular Weight	419.92 g/mol
Synonyms	8-Chloro-6-(1-methyl-4-piperidyl)-6H-dibenz[b,e][1,4]oxathiepin Hydrogen Maleate; 8-Chloro-6-(1-methylpiperidin-4-yl)-6H-dibenzo[b,e][1,4]oxathiepin Maleate; Zotepine Maleate; Zotepine Hydrogen Maleate; Lodopin (related to base form); Nipolept (related to base form); FR-1314 (Maleate salt); 6-(8-Chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)-1-methylpiperidin-4-ol Maleate (alternative naming)
EINECS	Contact for details

Quality Control

Our 8-Chloro-6-(1-Methyl-4-Piperidyl)-6H-Dibenz(B,E)-1,4-Oxathiepin Hydrog En Maleate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, to ensure compliance with stringent specifications suitable for pharmaceutical R&D and intermediate use. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.