Description

(D-Ala2,D-Pro4,Tyr5)-β-Casomorphin (1-5) Amide is a synthetic, modified pentapeptide analog of the endogenous opioid peptide β-casomorphin. This compound is of significant interest for its enhanced metabolic stability and receptor selectivity compared to its natural counterpart, making it a valuable research tool. It is primarily utilized by pharmaceutical researchers and life science companies in the development and study of opioid receptor function, pain management pathways, and neuropharmacology.

Application

• Biomedical Research: A critical reference standard and active probe in studies of the mu-opioid receptor (MOR) signaling and function.
• Pharmacology Development: Used in preclinical research for investigating novel analgesic compounds and understanding structure-activity relationships (SAR) of opioid peptides.
• Neuroscience Studies: Employed in vitro and in vivo to explore the role of opioid peptides in the central nervous system, including pain modulation and behavioral effects.
• Biochemical Assays: Serves as a ligand in competitive binding assays and functional tests to screen for new receptor agonists or antagonists.
• Academic Research: Utilized in university and institutional labs for fundamental research on peptide chemistry, stability, and bioactivity.

Basic Information

Product Name	(D-Ala2,D-Pro4,Tyr5)-β-Casomorphin (1-5) Amide
CAS No.	83936-24-7
Molecular Formula	C30H41N7O7
Molecular Weight	611.69 g/mol
Synonyms	β-Casomorphin (1-5) amide, [D-Ala², D-Pro⁴, Tyr⁵]-; H-Tyr-D-Ala-Phe-D-Pro-Tyr-NH₂; D-Ala2, D-Pro4, Tyr5-β-Casomorphin (1-5) amide; BCM (1-5) amide analog; [D-Ala², D-Pro⁴, Tyr⁵]β-Casomorphin-5-NH₂; Opioid peptide fragment 1-5 amide derivative; Tyr-D-Ala-Phe-D-Pro-Tyr-amide
EINECS	Contact for details

Quality Control

Our (D-Ala2,D-Pro4,Tyr5)-β-Casomorphin (1-5) Amide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in DMSO, acetic acid; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.