Description

Biphalin CAS NO 83916-01-2 is a synthetic opioid peptide dimer with potent analgesic properties, acting as a dual agonist for mu and delta opioid receptors. Its primary value lies in its high potency and prolonged duration of action compared to monomeric enkephalins, making it a critical research tool for studying pain pathways and receptor mechanisms. This compound is essential for pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on neuroscience, analgesic drug discovery, and neuropharmacology.

Application

• Neuroscience Research: Used as a potent reference standard in studies of opioid receptor binding, activation, and signaling pathways.
• Analgesic Drug Development: Serves as a key pharmacological tool for screening and evaluating new analgesic compounds and delivery systems.
• Pain Mechanism Studies: Employed in in vitro and in vivo models to investigate central and peripheral pain modulation.
• Receptor Pharmacology: Critical for characterizing the functional activity and selectivity of mu and delta opioid receptor subtypes.
• Biochemical Assays: Used in competitive binding assays and functional tests (e.g., GTPγS) to determine receptor affinity and efficacy.
• Peptide Chemistry Reference: Acts as a model compound in studies of peptide stability, metabolism, and blood-brain barrier penetration.

Basic Information

Product Name	Biphalin
CAS No.	83916-01-2
Molecular Formula	C44H58N10O11
Molecular Weight	878.99 g/mol
Synonyms	Tyr-D-Ala-Gly-Phe-NH-NH-Phe-Gly-D-Ala-Tyr; H-Tyr-D-Ala-Gly-Phe-NH-NH-Phe-Gly-D-Ala-Tyr-OH; [D-Ala2]Biphalin; Tyr-D-Ala-Gly-Phe-NH-NH<-Phe-Gly-D-Ala-Tyr; Opioid peptide dimer biphalin; Biphalin (Tyr-D-Ala-Gly-Phe-NH-NH-Phe-Gly-D-Ala-Tyr)
EINECS	Contact for details

Quality Control

Our Biphalin is manufactured under strict quality management systems to ensure the highest standards of purity and consistency for research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant guidelines for research-grade peptides, ensuring reliable and reproducible performance in your critical experiments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic (moisture-sensitive) nature, the product should be allowed to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular weight
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 2.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.