Description

Ac-Phe-Nle-Arg-Phe-Nh2 Acetate Salt is a synthetic peptide derivative of significant interest in advanced biochemical research and development. This compound serves as a critical tool for studying protease interactions, receptor binding, and signal transduction pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on peptide-based therapeutic discovery and diagnostic assay development.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic assays to study the kinetics and specificity of proteases like trypsin and related serine proteases.
• Pharmaceutical R&D: Serves as a key intermediate or reference standard in the discovery and development of novel peptide-based drugs targeting metabolic and neurological disorders.
• Diagnostic Development: Employed in the formulation of calibration standards and controls for clinical diagnostic kits that measure protease activity.
• Cell Biology Studies: Utilized to investigate cell signaling mechanisms and receptor-ligand interactions in vitro.
• Peptide Library Synthesis: Acts as a building block or template for constructing focused peptide libraries for high-throughput screening.

Basic Information

Product Name	Ac-Phe-Nle-Arg-Phe-Nh2 Acetate Salt
CAS No.	83903-28-0
Molecular Formula	C41H62N10O7 • xC2H4O2
Molecular Weight	~807.0 g/mol (free base)
Synonyms	Acetyl-Phenylalanyl-Norleucyl-Arginyl-Phenylalaninamide Acetate; N-Acetyl-Phe-Nle-Arg-Phe-NH2 Acetate; Ac-F-Nle-R-F-NH2 Acetate; Protease Substrate Analog; Trypsin Inhibitor Peptide; CAS 83903-28-0; H-Phe-Nle-Arg-Phe-NH2 Acetylated Acetate Salt
EINECS	Contact for details

Quality Control

Our Ac-Phe-Nle-Arg-Phe-Nh2 Acetate Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC/Titration)	1.0 - 3.0 eq
Peptide Content (AAA)	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.