Description

Glucagon, Oxindolyl-Ala(25)- CAS NO 83874-24-2 is a synthetic, site-specifically modified peptide analog of the glucagon hormone. This compound is of significant interest for advanced pharmaceutical research and development, particularly in the study of metabolic pathways and receptor interactions. It is primarily utilized by research institutions and pharmaceutical companies engaged in endocrinology, diabetes research, and the development of novel peptide-based therapeutics.

Application

• Pharmaceutical Research & Development: Serves as a critical reference standard and active ingredient in the development of novel glucagon receptor modulators.
• Metabolic Disorder Studies: Used in in vitro and in vivo research to investigate glucose metabolism, hepatic function, and diabetes mechanisms.
• Biochemical Assay Development: Employed as a high-purity ligand in receptor binding assays (RBA) and other analytical methods to study peptide-receptor interactions.
• Peptide Chemistry & Conjugation: Acts as a model compound for studying peptide stability, modification techniques, and structure-activity relationships (SAR).
• Academic Research: Utilized in university and institutional labs for fundamental research in endocrinology and peptide science.

Basic Information

Product Name	Glucagon, Oxindolyl-Ala(25)-
CAS No.	83874-24-2
Molecular Formula	C153H225N43O49S
Molecular Weight	3485.7 g/mol
Synonyms	[Oxindolylalanine25]-Glucagon; Glucagon (1-29), 25-L-3-(2-Oxo-1H-indol-3-yl)alanine-; 25-Oxindolylalanine-Glucagon; Glucagon analog with Oxindolyl-Ala at position 25; H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH (Oxindolyl-Ala25); Glucagon Oxindolyl-Ala(25) Peptide; Research Grade Glucagon Analog
EINECS	Contact for details

Quality Control

Our Glucagon, Oxindolyl-Ala(25)- is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters. We adhere to industry-standard analytical protocols, including HPLC and MS, to guarantee product integrity.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in dilute acetic acid or alkaline buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.