Description

2-Dimethylamino-4-(4-Fluorophenyl)Pyrimidine is a specialized pyrimidine derivative, a key heterocyclic building block in advanced organic synthesis. This compound matters for its role as a crucial intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique structure enables precise molecular modifications. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in kinase inhibitor research and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides where the pyrimidine core provides specific biological activity.
• Fine Chemical Production: Serves as a versatile precursor for creating complex molecules in custom synthesis and material science research.
• Research & Development (R&D): Essential for medicinal chemistry programs in academic and industrial labs for structure-activity relationship (SAR) studies.
• Ligand and Catalyst Development: Potential use in constructing specialized ligands for metal complexes and catalysts used in asymmetric synthesis.

Basic Information

Product Name	2-Dimethylamino-4-(4-Fluorophenyl)Pyrimidine
CAS No.	83858-07-5
Molecular Formula	C12H12FN3
Molecular Weight	217.24 g/mol
Synonyms	4-(4-Fluorophenyl)-2-(dimethylamino)pyrimidine; 2-(Dimethylamino)-4-(4-fluorophenyl)pyrimidine; 4-(p-Fluorophenyl)-2-(dimethylamino)pyrimidine; 83858-07-5; 2-Dimethylamino-4-(4-fluorophenyl)-pyrimidine; 2-N,N-Dimethylamino-4-(4-fluorophenyl)pyrimidine
EINECS	Contact for details

Quality Control

Our 2-Dimethylamino-4-(4-Fluorophenyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.