Description

Mast Cell Degranulating Peptide is a synthetic peptide that specifically triggers the release of inflammatory mediators from mast cells. This compound is a critical research tool for studying allergic responses, immune system signaling, and inflammatory pathways. It is primarily utilized by pharmaceutical researchers, immunologists, and academic institutions engaged in preclinical studies for asthma, allergy, and autoimmune disease research.

Application

• Immunological Research: A key reagent for in vitro and in vivo studies of mast cell activation, degranulation mechanisms, and histamine release.
• Allergy & Asthma Models: Used to induce and study allergic reactions in animal models to evaluate potential therapeutic compounds.
• Drug Discovery & Screening: Employed in high-throughput screening assays to identify novel mast cell stabilizers or anti-allergic agents.
• Inflammation Studies: Facilitates research into the role of mast cells in chronic inflammatory conditions and autoimmune disorders.
• Biomarker Investigation: Helps in understanding the release of specific proteases and cytokines from mast cells as potential disease biomarkers.
• Toxicology & Safety Pharmacology: Applied in studies assessing the potential of new chemical entities to cause pseudo-allergic reactions.

Basic Information

Product Name	Mast Cell Degranulating Peptide
CAS No.	83856-13-7
Molecular Formula	C78H122N24O19S2
Molecular Weight	1724.1 g/mol
Synonyms	MCD Peptide; Mastoparan; Mast Cell Degranulating Factor; Peptide 401; Wasp Venom Peptide MCDP; Mast Cell Degranulator; [Ile6]-Mastoparan; Polistes Mastoparan
EINECS	Contact for details

Quality Control

Our Mast Cell Degranulating Peptide is manufactured under strict quality systems to ensure batch-to-batch consistency and reliability for critical research. Each lot undergoes comprehensive analytical testing, including HPLC for purity and mass spectrometry for identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, peptide content, and solvent residues.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture absorption. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.