Description

Glutaryl-Alanyl-Alanyl-Alanyl-Ethylamide is a synthetic tetrapeptide derivative, specifically a glutaryl-modified peptide sequence. This compound is of significant interest in advanced biochemical research and pharmaceutical development due to its role as a model substrate or intermediate for studying enzyme kinetics, protease specificity, and peptide-based drug design. It serves the needs of research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on peptide chemistry and proteomics.

Application

• Protease & Enzyme Research: Used as a specific synthetic substrate to investigate the activity, inhibition, and catalytic mechanisms of various proteolytic enzymes, including serine and cysteine proteases.
• Pharmaceutical Intermediate: Serves as a key building block or precursor in the synthesis of more complex peptide-based active pharmaceutical ingredients (APIs) and diagnostic agents.
• Biochemical Assay Development: Employed in the development and validation of high-throughput screening (HTS) assays for drug discovery programs targeting protease-related diseases.
• Academic Research: A valuable tool in university and institutional labs for fundamental studies in peptide stability, metabolism, and structure-activity relationships (SAR).
• Reference Standard: Can be utilized as a certified reference material (CRM) or analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Glutaryl-Alanyl-Alanyl-Alanyl-Ethylamide
CAS No.	83808-35-9
Molecular Formula	C21H36N6O7
Molecular Weight	484.55 g/mol
Synonyms	Glutaryl-AAAA-ethylamide; Glutaryl-Ala-Ala-Ala-Ala-NH-Et; Nα-Glutaryl-L-alanyl-L-alanyl-L-alanyl-L-alanine ethylamide; GAAAA-NH-Et; Tetrapeptide substrate GAAAA; N-(1-Oxo-5-glutaryl)tetraalanine ethylamide; Ala-Ala-Ala-Ala-Glutaryl ethylamide
EINECS	Contact for details

Quality Control

Our Glutaryl-Alanyl-Alanyl-Alanyl-Ethylamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.