Description

1H-Indene, 5-Fluoro-2,3-Dihydro-6-Methoxy- is a high-purity fluorinated indene derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique molecular scaffold, which enables the construction of complex pharmacophores and functional materials. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific fluorine and methoxy substitutions into target molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of new-generation herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for organic electronic materials, such as semiconductors and light-emitting diodes (OLEDs), due to its conjugated indene core.
• Ligand and Catalyst Development: Employed in creating specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Studies: A valuable substrate for investigating new fluorination reactions and studying structure-activity relationships (SAR).
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes.

Basic Information

Product Name	1H-Indene, 5-Fluoro-2,3-Dihydro-6-Methoxy-
CAS No.	83802-72-6
Molecular Formula	C10H9FO
Molecular Weight	164.18 g/mol
Synonyms	5-Fluoro-6-methoxy-2,3-dihydro-1H-indene; 6-Methoxy-5-fluoroindane; 5-Fluoro-6-methoxyindane; 83802-72-6; 5-Fluoro-2,3-dihydro-6-methoxy-1H-indene; 5-Fluoro-6-methoxy-2,3-dihydroindene; 1H-Indene, 5-fluoro-2,3-dihydro-6-methoxy-
EINECS	Contact for details

Quality Control

Our 1H-Indene, 5-Fluoro-2,3-Dihydro-6-Methoxy- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with client specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.