Description

4-Amino-3-o-[2-Amino-2,3,4,6-Tetradeoxy-6-(Methylamino)-α-D-Erythro-Hexopyranosyl]-1,4,5-Trideoxy-1-[[(Formylamino)Acetyl]Methylamino]-6-o-Methyl-L-Chiro-Inositol is a complex, high-purity aminoglycoside derivative with significant biological activity. This compound is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel antibiotics and the study of bacterial resistance mechanisms. It serves as a key intermediate and reference standard for researchers and manufacturers in the life sciences sector.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of next-generation aminoglycoside antibiotics.
• Biochemical Research: Used as a reference standard and probe in studies of ribosomal targeting, protein synthesis inhibition, and mechanism of action.
• Antibiotic Development: Serves as a core structure for the development of novel antimicrobial agents to combat resistant bacterial strains.
• Analytical Standard: Provides a high-purity benchmark for quality control and method validation in analytical laboratories (HPLC, LC-MS).
• Microbiology Studies: Employed in research to understand and characterize bacterial resistance pathways to aminoglycosides.
• Medicinal Chemistry: A valuable scaffold for structure-activity relationship (SAR) studies to optimize potency and reduce toxicity.

Basic Information

Product Name	4-Amino-3-o-[2-Amino-2,3,4,6-Tetradeoxy-6-(Methylamino)-α-D-Erythro-Hexopyranosyl]-1,4,5-Trideoxy-1-[[(Formylamino)Acetyl]Methylamino]-6-o-Methyl-L-Chiro-Inositol
CAS No.	83728-96-5
Molecular Formula	C₂₀H₄₁N₇O₉
Molecular Weight	523.58 g/mol
Synonyms	L-Chiro-Inositol, 4-amino-3-O-[2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-α-D-erythro-hexopyranosyl]-1,4,5-trideoxy-1-[[(formylamino)acetyl]methylamino]-6-O-methyl-; 6'-N-Methyl-4'-deoxy-6'-epi-sisomicin derivative; Antibiotic G 418 related compound; Geneticin analogue; A complex sisomicin/gentamicin-type aminoglycoside intermediate.
EINECS	Contact for details

Quality Control

Our 4-Amino-3-o-[2-Amino-2,3,4,6-Tetradeoxy-6-(Methylamino)-α-D-Erythro-Hexopyranosyl]-1,4,5-Trideoxy-1-[[(Formylamino)Acetyl]Methylamino]-6-o-Methyl-L-Chiro-Inositol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.