Description

Calcitonin Gene-Related Peptide (CGRP) is a potent 37-amino acid neuropeptide that plays a critical role in vasodilation and neurotransmission. This compound is of significant interest for its role in migraine pathophysiology and as a key target for therapeutic development. It is essential for researchers and developers in the pharmaceutical and biotechnology sectors focused on neuroscience, cardiovascular research, and novel drug discovery. The product is supplied as a high-purity material to support rigorous scientific and pre-clinical applications.

Application

• Neuroscience Research: Fundamental studies on pain signaling, migraine mechanisms, and neurogenic inflammation.
• Cardiovascular Research: Investigation of vascular tone, blood pressure regulation, and coronary blood flow.
• Pharmaceutical Development: Key reference standard and target molecule for the development of CGRP receptor antagonists and monoclonal antibodies for migraine therapy.
• Biomarker Studies: Utilization in assay development for measuring CGRP levels in clinical and pre-clinical samples.
• Cell Signaling & Molecular Biology: Studies of G-protein coupled receptor (GPCR) pathways and intracellular signaling cascades.
• Academic & Institutional Research: A vital reagent for universities and research institutes exploring neurovascular biology.

Basic Information

Product Name	Calcitonin Gene-Related Peptide
CAS No.	83652-28-2
Molecular Formula	C164H263N51O53S2
Molecular Weight	3790.3 g/mol
Synonyms	CGRP; Calcitonin Gene-Related Peptide, human; CGRP-I; α-CGRP; Calcitonin gene-related peptide 1; hCGRPα; CALCA (83-119), human; α-Type Calcitonin Gene-Related Peptide
EINECS	Contact for details

Quality Control

Our Calcitonin Gene-Related Peptide is produced and tested to meet high standards for research and development. Each batch undergoes rigorous analytical characterization, including HPLC for purity and MS for identity confirmation. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We adhere to strict quality management protocols to ensure consistency, reliability, and traceability for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be kept in a dry environment. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.